Ipamorelin is a pentapeptide somewhat similar to Hexarelin but it is comparatively clean and safe. It also has some similarities to GHRP-2 or GHRP-6 but devoid of the food craving issue. Peptides need to be slow and steady in its release especially mimicking GH times of release. It can help keep down side effects. Ipamorelin here works like ghrelin mimetic but has gone to show more stability in containing somatostatin and initiating the GH release. In this way it is different from GHRP-6. The relationship between proteins, amino acids and peptides can be analyzed at https://www2.chemistry.msu.edu/faculty/reusch/virttxtjml/proteins.htm
Benefits of iPamorelin When taken in lower dosage you do not see any spikes in prolactin or cortisol. It helps in reducing body fat in test animals. It has also soon increase in LBM in lab animals. Strangely it has soon anti aging properties in animals and has also improved the mood and sleep.
iPamorelin Profile iPamorelin is a mild GHRP but this does not mean they do have less potential. This pentapeptide can increase GH pulse and comes with very less side effects. It is tested in the lab that iPamorelin can work at 1200mcgs per day without breaking the desensitization levels. Moreover studies reveal that even a large dose of iPamorelin does not show any effects on the natural GH production. It is also believed that it has similar characteristic of GHRP-6 and displayed an increase in gastric mobility and ghrelin in test animals primarily targeting selective GH pulse. The good news is it does not stimulate hunger.
Side effects of iPamorelin Despite iPamorelin considered to be safe with least side effects on test animals especially outside the GHRP family it does have side effects. It attacks GH release particularly GHRP-6 but it does not affect blood serum plasma levels in animals. Theoretically, high dose of iPamorelin can lead to increase in acetylcholine and cortisol. But when iPamorelin is the only GHRP there is no increase in both acetylcholine and cortisol blood plasma levels. This fact is true even if the dose is higher in comparison with growth hormone releases.
Functioning of Ipamorelin It is researched in animals that iPamorelin increases synthesis of the cell and improve secretion in the pancreatic tissues. It also stimulates ghrelin in stomach. All this leads to release of GH and helps in controlling hunger, it is studied. Moreover it helps in fat loss by reorganizing nutrients and building body mass in the test animals.
Ipamorelin is similarly in form to other peptides. It is available as freeze dried powder and is delicate. It has to be stored in a cool and dry place. But before reconstituting, it has to be brought to the room temperature. After reconstituting with bacteriostatic water it has to be again stored in a cool and dry place like a refrigerator. It can be administers to test animals using insulin syringes, as it is administered subcutaneously. In case of prolactin issues using products that can reduce estrogen and prolactin symptoms is advised. Some of these include Aromasin, Letrozole, Arimidex from the aromatase inhibitor category and anti-prolactin’s like Cabergoline or Dostinex.